Abstract

The eukaryotic multi-subunit Mediator complex coordinates between transcription activators/repressors and general transcription machinery to direct a rigid transcriptional regulation. In plants, investigations on the Mediator complex have gained pace recently. Several reports from Arabidopsis and other plants provide details of the structure and function of the Mediator complex/subunits. Plant Mediator complex subunits are encoded by multiple paralogous genes and form a complex network regulating diverse aspects of plant growth and development. Different subunits of the Mediator complex are shown to have diverse roles in shaping overall plant architecture and involve multiple hormonal signals. The critical role of the Mediator complex subunits is evident in both the vegetative and reproductive phases of plants. It also mediates metabolite homeostasis and non-coding RNA production. While functional conservation has been attributed to several subunits of the Mediator complex, diverse mechanistic aspects are also emerging. The integration of new knowledge greatly improves our understanding of the complexity of transcriptional control of different traits in plants.

摘要

真核多亚基介导复合体在转录激活子/阻遏子和一般转录机制之间进行协调，以指导严格的转录调节。在植物中，对中介复合体的研究最近加快了步伐。拟南芥的一些报道和其他植物提供了介体复合体/亚基的结构和功能的详细信息。植物介体复合亚基由多个旁系同源基因编码，形成调节植物生长和发育各个方面的复杂网络。介体复合体的不同亚基在塑造整体植物结构中具有不同的作用，并涉及多种激素信号。介体复合体亚基的关键作用在植物的营养和繁殖阶段都很明显。它还介导代谢物稳态和非编码 RNA 的产生。虽然功能保护被归因于中介复合体的几个亚基，但不同的机制方面也正在出现。