Abstract

Ginkgo biloba leaf extract (EGBL) is a valuable herbal extract. The main active ingredients are flavonoids, terpene lactones, organic acids and proanthocyanidins. In recent years, there have been many reports on the detection of the above active ingredients. In this paper, the analysis methods of chemical components in EGBL were reviewed, such as ultraviolet spectrophotometry, high-performance liquid chromatography, and quantitative nuclear magnetic resonance. The analysis methods of ginkgolic acids are also reviewed. Based on the current research progress, three suggestions are provided. Firstly, the quality marker research of EGBL needs to be strengthened. Secondly, more bioassay methods for EGBL quality control should be developed. Thirdly, it is necessary to strengthen the detection of proanthocyanidins in EGBL.

摘要

银杏叶提取物（EGBL）是一种有价值的草药提取物。主要活性成分为黄酮类、萜内酯、有机酸和原花青素。近年来，关于上述活性成分的检测已有不少报道。本文综述了EGBL中化学成分的分析方法，如紫外分光光度法、高效液相色谱法、定量核磁共振法等。并对银杏酸的分析方法进行了综述。根据目前的研究进展，提出三点建议。首先，EGBL的质量标志研究有待加强。其次，应开发更多用于EGBL质量控制的生物测定方法。三是加强EGBL中原花青素的检测。