An ultrasound-assisted magnetic solid-phase extraction method was developed to pre-concentrate tetracyclines (TCs) in wastewater and river water. The magnetic chitosan-zeolite composite was used as an adsorbent. The morphological and structural properties of the adsorbent were characterised by various analytical techniques. The factors affecting the ultrasound-assisted magnetic solid-phase extraction method were optimised using a central composite design. A high performance liquid chromatography equipped with a photodiode array detector was used to quantify TCs in wastewater and river water samples. Under optimised parameters, the developed analytical approach gave acceptable linearity (LOQ-400 µg L−1) with correlation coefficients exceeding 0.993, while the detection and quantitation limits ranged from 0.05–0.67 and 0.14–2.03 µg L−1, respectively. Attained recoveries were 90–101%, with intraday and interday precision expressed as the relative standard deviation (%RSD) below 5%. Even though the target analytes (tetracycline, oxytetracycline and oxytetracycline) were not detected in environmental samples, the synthesised adsorbent was suitable for the isolation of TCs in a complex matrix resulting in an accurate, precise, rapid and sensitive analytical method.

中文翻译：

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磁性壳聚糖-沸石复合材料作为超声辅助磁力固相萃取水样中四环素的吸附剂

开发了一种超声辅助磁固相萃取方法来预浓缩废水和河水中的四环素 (TC)。采用磁性壳聚糖-沸石复合材料作为吸附剂。通过各种分析技术表征了吸附剂的形态和结构特性。采用中心组合设计对影响超声辅助磁力固相萃取方法的因素进行了优化。使用配备光电二极管阵列检测器的高效液相色谱法对废水和河水样品中的TC进行定量。在优化参数下，所开发的分析方法具有可接受的线性度（LOQ-400 µg L−1），相关系数超过0.993，而检测限和定量限分别为0.05–0.67和0.14–2.03 µg L−1。回收率为 90-101%，日内和日间精密度表示为相对标准偏差 (%RSD) 低于 5%。尽管在环境样品中未检测到目标分析物（四环素、土霉素和土霉素），但合成的吸附剂适合分离复杂基质中的TC，从而形成准确、精确、快速和灵敏的分析方法。