Extended wireless pH monitoring (WPM) is used to investigate gastroesophageal reflux disease (GERD) as subsequent or alternative investigation to 24-hour catheter-based studies. However, false negative catheter studies may occur in patients with intermittent reflux or due to catheter-induced discomfort or altered behavior. We aim to investigate the diagnostic yield of WPM after a negative 24-hour multichannel intraluminal impedance pH (MII-pH) monitoring study and to determine predictors of GERD on WPM given a negative MII-pH.

中文翻译：

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扩展的无线 pH 监测可显着提高 pH 阻抗研究正常的患者的胃食管反流病诊断率。

扩展无线 pH 监测 (WPM) 用于研究胃食管反流病 (GERD)，作为 24 小时导管研究的后续或替代研究。然而，假阴性导管研究可能发生在间歇性反流的患者中，或者由于导管引起的不适或行为改变。我们的目的是调查 24 小时多通道管腔内阻抗 pH (MII-pH) 负监测研究后 WPM 的诊断率，并在 MII-pH 为负的情况下确定 WPM 上 GERD 的预测因子。