Mapping cellular response to destabilized transthyretin reveals cell- and amyloidogenic protein-specific signatures,Amyloid

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Mapping cellular response to destabilized transthyretin reveals cell- and amyloidogenic protein-specific signatures
Amyloid ( IF 5.5 ) Pub Date : 2023-07-13 , DOI: 10.1080/13506129.2023.2224494
Sabrina Ghosh _{1,

2} , Carlos Villacorta-Martin ₁ , Jonathan Lindstrom-Vautrin ₁ , Devin Kenney ₁ , Carly S Golden ₁ , Camille V Edwards _{1,

2,

3} , Vaishali Sanchorawala _{2,

3} , Lawreen H Connors ₃ , Richard M Giadone _{1,

2} , George J Murphy _{1,

2}

Affiliation

In ATTR amyloidosis, transthyretin (TTR) protein is secreted from the liver and deposited as toxic aggregates at downstream target tissues. Despite recent advancements in treatments for ATTR amyloi...

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