Objective:Anxiety is among the most common psychiatric illnesses, and it commonly co-occurs with epilepsy. This review of the existing literature on anxiety comorbid with epilepsy aims to generate new insights into strategies for assessment and treatment.Methods:The authors conducted a narrative literature review to select key publications that help clarify the phenomenology and management of comorbid anxiety and epilepsy.Results:Anxiety symptoms may be relevant even if the criteria for a diagnosis of an anxiety disorder are not met. Associating specific seizure types or seizure localization with anxiety symptoms remains difficult; however, the amygdala is a brain region commonly associated with seizure foci and panic or fear sensations. The hypothalamic-pituitary-adrenal axis may also be relevant for anxiety symptoms, particularly for the selection of treatments. Nonpharmacological treatment is appropriate for anxiety comorbid with epilepsy, particularly because relaxation techniques may reduce hypersympathetic states, which improve symptoms. Medication options include antidepressants and anticonvulsants that may have efficacy for anxiety symptoms. Benzodiazepines are a good choice to address this comorbid condition, although side effects may limit utility.Conclusions:Ultimately, there are numerous treatment options, and although there is a limited evidence base, quality of life may be improved with appropriate treatment for individuals experiencing comorbid anxiety and epilepsy.

中文翻译：

---

共病焦虑和癫痫的治疗。

目的：焦虑是最常见的精神疾病之一，通常与癫痫同时发生。本文对有关焦虑与癫痫共病的现有文献进行综述，旨在对评估和治疗策略产生新的见解。方法：作者进行了叙述性文献综述，以选择有助于阐明焦虑和癫痫共病的现象学和管理的关键出版物。结果：即使不符合焦虑症的诊断标准，焦虑症状也可能是相关的。将特定的癫痫发作类型或癫痫发作定位与焦虑症状联系起来仍然很困难；然而，杏仁核是一个通常与癫痫灶和恐慌或恐惧感相关的大脑区域。下丘脑-垂体-肾上腺轴也可能与焦虑症状有关，特别是与治疗的选择有关。非药物治疗适用于伴有癫痫的焦虑症，特别是因为放松技巧可以减少交感神经过度状态，从而改善症状。药物选择包括可能对焦虑症状有效的抗抑郁药和抗惊厥药。苯二氮卓类药物是解决这种合并症的一个不错的选择，尽管副作用可能会限制实用性。结论：最终，有多种治疗选择，尽管证据基础有限，但通过对患有合并症的个体进行适当的治疗，可以改善生活质量焦虑和癫痫。