BACKGROUND Elderly patients with aortic stenosis (AS) not only have a reduced life expectancy but also a reduced quality of life (QoL). The benefits of an AS intervention may be considered a balance between a good QoL and a reasonably extended life. However, the different questionnaires being used to determine the QoL, were generally not developed for the specific situation of patients with AS and come with strengths and considerable weaknesses. The objective of this manuscript was to provide an overview of the available QoL instruments in AS research, describe their strengths and weaknesses, and to provide our assessment of the utility of the available scoring instruments for QoL measurements in AS. SUMMARY We identified and reviewed the following instruments that are used in AS research: Short Form Health Survey (SF-36/SF-12), EuroQol-5D (EQ-5D), the Illness Intrusiveness Rating Scale (IIRS), the HeartQoL, the Kansas City Cardiomyopathy Questionnaire (KCCQ), the Minnesota Living with Heart Failure Questionnaire (MLHF), the MacNew Questionnaire, and the Toronto Aortic Stenosis Quality of Life Questionnaire (TASQ). KEY MESSAGES There is no standardized assessment of QoL in patients with AS. Many different questionaires are being used, but they are rarely specific for AS. There is a need for AS specific research into the QoL of patients as life prolongation may compete for an improved QoL in this elderly patient group.

中文翻译：

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主动脉瓣狭窄研究中的生活质量测量：叙述性回顾。

背景 患有主动脉瓣狭窄（AS）的老年患者不仅预期寿命缩短，而且生活质量（QoL）降低。AS 干预的好处可以被认为是良好的生活质量和合理延长寿命之间的平衡。然而，用于确定生活质量的不同问卷通常不是针对 AS 患者的具体情况而开发的，并且各有优点和相当大的缺点。本手稿的目的是概述 AS 研究中可用的生活质量工具，描述它们的优点和缺点，并提供我们对可用的 AS 生活质量测量评分工具的实用性的评估。摘要 我们确定并审查了 AS 研究中使用的以下工具：简短健康调查 (SF-36/SF-12)、EuroQol-5D (EQ-5D)、疾病侵入性评定量表 (IIRS)、HeartQoL、堪萨斯城心肌病问卷 (KCCQ)、明尼苏达心力衰竭问卷 (MLHF)、MacNew 问卷和多伦多主动脉瓣狭窄生活质量问卷（TASQ）。关键信息 目前尚无 AS 患者生活质量的标准化评估。人们使用了许多不同的问卷，但它们很少专门针对 AS。有必要对 AS 患者的生活质量进行专门研究，因为在这一老年患者群体中，寿命的延长可能会影响生活质量的改善。和多伦多主动脉瓣狭窄生活质量问卷（TASQ）。关键信息 目前尚无 AS 患者生活质量的标准化评估。人们使用了许多不同的问卷，但它们很少专门针对 AS。有必要对 AS 患者的生活质量进行专门研究，因为在这一老年患者群体中，寿命的延长可能会影响生活质量的改善。和多伦多主动脉瓣狭窄生活质量问卷（TASQ）。关键信息 目前尚无 AS 患者生活质量的标准化评估。人们使用了许多不同的问卷，但它们很少专门针对 AS。有必要对 AS 患者的生活质量进行专门研究，因为在这一老年患者群体中，寿命的延长可能会影响生活质量的改善。