Pulmonary drug delivery is complex due to several challenges including disease-, patient-, and clinicians-related factors. Although many inhaled medications are available in aerosol medicine, delivering aerosolized medications to patients requires effective disease management. There is a large gap in the knowledge of clinicians who select and provide instructions for the correct use of aerosol devices. Since improper device selection, incorrect inhaler technique, and poor patient adherence to prescribed medications may result in inadequate disease control, individualized aerosol medicine is essential for effective disease management and control. The components of individualized aerosol medicine include: (1) Selecting the right device, (2) Selecting the right interface, (3) Educating the patient effectively, and (4) Increasing patient adherence to therapy. This paper reviews each of these components and provides recommendations to integrate the device and interface into the patient for better clinical outcomes.

中文翻译：

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个体化气雾剂药物：将装置融入患者体内

由于疾病、患者和临床医生相关因素等多种挑战，肺部药物输送非常复杂。尽管许多吸入药物可用于气雾剂药物，但向患者提供雾化药物需要有效的疾病管理。选择并提供正确使用气雾剂装置说明的临床医生的知识存在很大差距。由于设备选择不当、吸入器技术不正确以及患者对处方药物的依从性差可能导致疾病控制不足，因此个体化气雾剂药物对于有效的疾病管理和控制至关重要。个体化气雾医学的组成部分包括：(1) 选择正确的设备，(2) 选择正确的接口，(3) 有效地教育患者，以及 (4) 提高患者对治疗的依从性。本文回顾了这些组件中的每一个，并提供了将设备和接口集成到患者体内以获得更好的临床结果的建议。