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Treatment response and neurofilament light chain levels with long-term patisiran in hereditary transthyretin-mediated amyloidosis with polyneuropathy: 24-month results of an open-label extension study
Amyloid ( IF 5.5 ) Pub Date : 2023-07-20 , DOI: 10.1080/13506129.2023.2232520
Simina Ticau 1 , Emre Aldinc 1 , Michael Polydefkis 2 , David Adams 3 , Teresa Coelho 4 , Mitsuharu Ueda 5 , Cecilia Hale 1 , John Vest 1 , Paul Nioi 1 ,
Affiliation  

Longitudinal changes in neurofilament light chain (NfL) levels were evaluated alongside prespecified clinical assessments 24 months into the patisiran Global open-label extension (OLE) study in pat...

中文翻译:

长期 patisiran 对遗传性转甲状腺素蛋白介导的淀粉样变性伴多发性神经病的治疗反应和神经丝轻链水平:开放标签扩展研究的 24 个月结果

在帕蒂西兰全球开放标签延伸 (OLE) 研究 24 个月后,神经丝轻链 (NfL) 水平的纵向变化与预先指定的临床评估一起进行了评估。
更新日期:2023-07-20
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