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Analysis of postpartum hypertension in women with preeclampsia
Journal of Human Hypertension ( IF 2.7 ) Pub Date : 2023-07-22 , DOI: 10.1038/s41371-023-00849-3
Qinqin Xue 1 , Guang Li 1 , Yanyun Gao 1 , Yunjing Deng 1 , Bianju Xu 1 , Yu Chen 1 , Yu Gao 1 , Qi Chen 2
Affiliation  

Postpartum hypertension including persistent and recurrent hypertension could significantly affect maternal morbidity in preeclampsia. Data on the postpartum management of women with preeclampsia is limited. The objective of this study was to investigate the details of women experiencing persistent postpartum hypertension (PerPPH) or developing recurrent postpartum hypertension (RecPPH) after birth and whether the treatment with anti-hypertensive drugs could shorten the hospital stay. We also compared the clinical parameters in women who developed RecPPH and who did not. Data on 188 preeclamptic women, including the severity or time of onset, duration of hospital admission postpartum, and blood pressure during the admission were collected and analyzed. Overall, 30% of preeclamptic women developed RecPPH on day 1, 13% on day 3, and 12% on day 5 after birth. Women with severe preeclampsia or early onset preeclampsia are more likely to develop RecPPH, compared to women with mild or late onset preeclampsia. The overall time in days before discharge was not different between women with normal blood pressure and women with abnormal blood pressure 1 h after birth, regardless of the severity or gestation of onset. However, women with severe or early onset preeclampsia stayed longer in the hospital, compared to women with mild or late onset preeclampsia. In addition, women with severe or early onset preeclampsia or early delivery increased risk of developing RecPPH. In conclusion, we demonstrate that RecPPH became apparent on day 1 after delivery, and hence close monitoring of blood pressure even if initially seemingly normal after birth is important.



中文翻译:

子痫前期女性产后高血压的分析

产后高血压,包括持续性和复发性高血压,可显着影响先兆子痫的孕产妇发病率。有关先兆子痫女性产后管理的数据有限。本研究的目的是调查患有持续性产后高血压(PerPPH)或产后复发性产后高血压(RecPPH)的女性的详细情况,以及抗高血压药物治疗是否可以缩短住院时间。我们还比较了患有 RecPPH 和未患有 RecPPH 的女性的临床参数。收集并分析了 188 名先兆子痫女性的数据,包括严重程度或发病时间、产后入院持续时间以及入院期间的血压。总体而言,30% 的先兆子痫女性在出生后第 1 天出现 RecPPH,13% 在第 3 天出现 RecPPH,12% 在第 5 天出现 RecPPH。与轻度或晚发性子痫前期的女性相比,患有重度子痫前期或早发性子痫前期的女性更容易患 RecPPH。无论发病的严重程度或妊娠期如何,血压正常的女性和出生后 1 小时血压异常的女性在出院前的总时间(天数)没有差异。然而,与轻度或晚发性子痫前期的女性相比,患有严重或早发性子痫前期的女性住院时间更长。此外,患有严重或早发先兆子痫或早产的女性发生 RecPPH 的风险增加。总之,我们证明 RecPPH 在产后第 1 天变得明显,因此即使出生后最初看似正常,密切监测血压也很重要。

更新日期:2023-07-22
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