ABSTRACT

Magnesium implants are susceptible to premature failure due to corrosion and cyclic loading within the body. Composite fibre coatings are effective at reducing corrosion in magnesium materials. In this study, an Mg/HA composite was fabricated, and microscopic and mechanical characterisation was performed. The samples were then electrospun with PCL/2.5%HA fibres, and corrosion behaviour was explored by immersion tests. Finally, rotary bending fatigue tests in air and SBF environments were conducted. According to the findings, the Mg/2.5%HA and coated Mg/2.5%HA samples can withstand more than 1 million cycles under 60 MPa. Compared to pure Mg, Mg/2.5%HA has better corrosion and corrosion fatigue resistance. Furthermore, a PCL/2.5%HA fibre coating can increase the corrosion fatigue resistance of Mg/2.5%HA as a result of the polymer scaffold, passive protective layer, and apatite adsorption capability. Results suggest that Mg/2.5%HA composites coated with PCL/2.5%HA fibres are potentially suitable for use in orthopaedic biomaterials.

摘要

由于体内的腐蚀和循环负荷，镁植入物很容易过早失效。复合纤维涂层可有效减少镁材料的腐蚀。在本研究中，制备了 Mg/HA 复合材料，并进行了微观和机械表征。然后用 PCL/2.5%HA 纤维对样品进行静电纺丝，并通过浸泡测试探索腐蚀行为。最后进行了空气和SBF环境下的旋转弯曲疲劳试验。研究结果显示，Mg/2.5%HA 和涂层 Mg/2.5%HA 样品可在 60 MPa 下承受超过 100 万次循环。与纯Mg相比，Mg/2.5%HA具有更好的耐腐蚀和腐蚀疲劳性能。此外，由于聚合物支架的作用，PCL/2.5%HA纤维涂层可以提高Mg/2.5%HA的耐腐蚀疲劳性能，钝化保护层，以及磷灰石吸附能力。结果表明，涂​​有 PCL/2.5%HA 纤维的 Mg/2.5%HA 复合材料可能适用于骨科生物材料。