This study investigated the anti-obesity effects of yuja pomace extract fermented with lactic acid bacteria in rats with high-fat diet-induced obesity over a period of eight weeks. Epididymal fat cell size was significantly smaller, by about 33%, in the treatment groups given yuja pomace extract fermented with lactic acid bacteria compared to the CON group. Electron microscopic observation of hepatocyte microstructure showed that the number of lipid droplets was lower in hepatocytes, the number of mitochondria was higher, along with distinct cristae, and the rough endoplasmic reticula were well developed with stacks of cisternae and ribosomes. Thus, it is believed that yuja pomace extract fermented with lactic acid bacteria, by influencing body weight and lipid accumulation, is effective in the prevention and treatment of obesity.

中文翻译：

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乳酸菌发酵柚子果渣提取物对大鼠肝细胞和附睾脂肪组织的抗肥胖作用

这项研究调查了用乳酸菌发酵的柚子果渣提取物对高脂肪饮食引起的肥胖大鼠的抗肥胖作用，为期八周。与 CON 组相比，给予乳酸菌发酵柚子果渣提取物的治疗组的附睾脂肪细胞尺寸显着减小，约减少 33%。肝细胞显微结构电镜观察显示，肝细胞内脂滴数量较少，线粒体数量较多，嵴清晰，粗面内质网发达，有细胞池和核糖体堆积。因此，据信用乳酸菌发酵的柚子果渣提取物通过影响体重和脂质积累，可有效预防和治疗肥胖。