ABSTRACT

This study examined longitudinal predictors of neurodevelopmental outcomes in children with Down syndrome (DS). Participants were assessed at Wave 1 during infancy on measures of looking behavior and caregivers provided infant sensory ratings. At Wave 2, child-age participants completed a developmental assessment and caregivers provided ratings of executive function, ADHD symptoms, and autism symptoms. Longer looking durations and greater sensory dysregulation during infancy were predictive of higher ADHD symptom ratings and other neurodevelopmental outcomes during childhood. The findings suggest that early indicators of neurodevelopmental dysregulation may be detectable during infancy in DS.

摘要

这项研究检查了唐氏综合症（DS）儿童神经发育结果的纵向预测因素。参与者在婴儿期的第一波中接受了外观行为测量的评估，护理人员提供了婴儿感官评级。在第二波中，儿童年龄参与者完成了发育评估，护理人员提供了执行功能、多动症症状和自闭症症状的评级。婴儿期较长的注视时间和较大的感觉失调预示着儿童期较高的多动症症状评级和其他神经发育结果。研究结果表明，神经发育失调的早期指标可能在 DS 婴儿期就可以检测到。