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Recent developments in the use of centrifugal spinning and pressurized gyration for biomedical applications
WIREs Nanomedicine and Nanobiotechnology ( IF 8.6 ) Pub Date : 2023-08-08 , DOI: 10.1002/wnan.1916
Jubair Ahmed 1 , Merve Gultekinoglu 2 , Mohan Edirisinghe 1
Affiliation  

Centrifugal spinning is a technology used to generate small diameter fibers and has been extensively studied for its vast applications in biomedical engineering. Centrifugal spinning is known for its rapid production rate and has inspired the creation of other technologies which leverage the high-speed rotation, namely Pressurized Gyration. Pressurized gyration incorporates a unique applied gas pressure which serves to provide additional control over the fiber production process. The resulting fibers are uniquely suitable for a range of healthcare-related applications that are thoroughly discussed in this work, which involve scaffolds for tissue engineering, solid dispersions for drug delivery, antimicrobial meshes for filtration and bandage-like fibrous coverings for wound healing. In this review, the notable recent developments in centrifugal spinning and pressurized gyration are presented and how these technologies are being used to further the range of uses of biomaterials engineering, for example the development of core-sheath fabrication techniques for multi-layered fibers and the combination with electrospinning to produce advanced fiber mats. The enormous potential of these technologies and their future advancements highlights how important they are in the biomedical discipline.

中文翻译:

离心旋转和加压回转在生物医学应用中的最新进展

离心纺丝是一种用于生成小直径纤维的技术,因其在生物医学工程中的广泛应用而受到广泛研究。离心纺丝以其快速的生产率而闻名,并激发了其他利用高速旋转的技术(即加压回转)的创建。加压回转结合了独特的施加气压,可对纤维生产过程提供额外的控制。由此产生的纤维特别适合一系列与医疗保健相关的应用,这些应用在本工作中进行了深入讨论,其中包括用于组织工程的支架、用于药物输送的固体分散体、用于过滤的抗菌网和用于伤口愈合的绷带状纤维覆盖物。在这篇综述中,介绍了离心纺丝和加压回转方面的最新进展,以及如何使用这些技术来进一步扩大生物材料工程的应用范围,例如多层纤维的芯鞘制造技术的发展和与静电纺丝相结合生产先进的纤维垫。这些技术的巨大潜力及其未来的进步凸显了它们在生物医学学科中的重要性。
更新日期:2023-08-08
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