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Evaluation of the Role of Preoperative Oral Amisulpride as Part of a Multimodal Antiemetic Prophylaxis Regime on Postoperative Nausea and Vomiting in Patients Undergoing Craniotomy: A Prospective, Double-Blind, Randomized, Placebo-controlled Study.
Journal of Neurosurgical Anesthesiology ( IF 3.7 ) Pub Date : 2023-08-22 , DOI: 10.1097/ana.0000000000000936
Anubha Gupta 1 , Devendra Gupta 1 , Pragya Gupta 1 , Rudrashish Haldar 1 , Ruchi Verma 1 , Prabhaker Mishra 2 , Shashi Srivastava 1
Affiliation  

Patients undergoing craniotomy are at high risk for postoperative nausea and vomiting (PONV) despite the use of prophylactic antiemetics. We hypothesized that a single preoperative oral dose of amisulpride as part of a multimodal antiemetic regimen would decrease the incidence of PONV in patients undergoing craniotomy for intracranial tumor surgery.

中文翻译:

评估术前口服氨磺必利作为多模式止吐预防方案的一部分对开颅手术患者术后恶心和呕吐的作用:一项前瞻性、双盲、随机、安慰剂对照研究。

尽管使用预防性止吐药,接受开颅手术的患者术后恶心呕吐 (PONV) 的风险很高。我们假设,术前单次口服氨磺必利作为多模式止吐方案的一部分,可以降低因颅内肿瘤手术开颅手术的患者 PONV 的发生率。
更新日期:2023-08-22
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