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The inverse association between the apolipoprotein E ε4 allele and C-reactive protein levels is stronger in persons with obesity and diabetes
Scandinavian Journal of Immunology ( IF 3.7 ) Pub Date : 2023-08-23 , DOI: 10.1111/sji.13323
Lasse Melvaer Giil 1, 2 , Silja Hanseth 1 , Ognjen Bojovic 3 , Jan Erik Nordrehaug 2 , Per Magne Ueland 4 , Klaus Meyer 4 , Grethe S Tell 5
Affiliation  

C-reactive protein (CRP) is lower in patients who carry the apolipoprotein E epsilon 4 allele variant (APOEε4) of the APOE gene. This could however be explained by other factors observed in APOEε4 carriers, such as lower body mass index (BMI), possibly less diabetes and more use of statins, all associated with CRP concentrations.

中文翻译:

肥胖和糖尿病患者的载脂蛋白 E ε4 等位基因与 C 反应蛋白水平之间的负相关性更强

携带载脂蛋白 E 的患者的 C 反应蛋白 (CRP) 较低epsilon 4 等位基因变异 (APOEε4) a>APOE 基因。然而,这可以通过在 APOEε4 携带者中观察到的其他因素来解释,例如较低的体重指数 (BMI)、可能较少的糖尿病和更多地使用他汀类药物,所有这些都与 CRP 浓度相关。
更新日期:2023-08-23
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