Excellent mechanical strength and biodegradable characteristics of magnesium alloys have sparked considerable interest in orthopedic applications. The utilization of magnesium alloys in orthopedic applications has been restricted due to their brittleness caused by high corrosion rate in biological environments. One of the best techniques for increasing corrosion resistance of these alloys is surface coating. For the first time, the present work aims to dip-coat zein-bioactive glass (BG) nanocomposite on AZ31B magnesium alloy. The alloy surface was also coated by native zein as a control coating. BG nanoparticles required for zein and BG (zein_BG) composite were synthesized by a bio-inspired method using cetyltrimethylammonium bromide (CTAB) as a template. The formation of BG particles was affirmed by FTIR showing characteristic Si-O-Si and Si-O^– peaks. Nano-size of BG particles with an average diameter of 6.67 ± 0.06 nm was reported by TEM. SEM micrographs revealed successful deposition of zein and zein_BG coatings on the magnesium alloy surfaces. High-resolution XPS analysis on zein_BG-coated Mg alloy immersed in HBSS revealed the corrosion deposition of Mg(OH)_2, MgHPO₄.H₂O, CaHPO₄.H₂O, SiO_2, MgCO₃, and CaCO₃ on the substrate surface. More than twofold wettability, 95% adhesion strength and 14-fold increase in surface roughness were reported for zein_BG-coated magnesium alloy compared to the bare surface. Measurements of weight loss in zein and zein_BG-coated alloy substrates in Hanks Balanced Salt Solution (HBSS) for 10 d at 37°C showed a drastic decrease in weight loss of substrates after coating. As a result, zein_BG-coated substrate was observed to possess the maximum protective efficacy (95.99%) against corrosion. Interestingly, electrochemical measurements revealed a vast decrease in corrosion current density (2.41 E⁻⁶ A.cm⁻²) of zein_BG-coated substrate compared to the uncoated substrate (3.04 E⁻⁴ A.cm⁻²). Electrochemical impedance spectra (EIS) confirmed capacitive behavior of zein_BG-coated alloy substrate. These findings demonstrated that simple zein_BG composite dip coating was a successful corrosion-resistant implant coating on magnesium alloy surface for orthopedic applications.

镁合金优异的机械强度和可生物降解的特性引起了人们对骨科应用的极大兴趣。由于生物环境中的高腐蚀速率导致镁合金脆性，镁合金在骨科应用中的应用受到限制。提高这些合金耐腐蚀性的最佳技术之一是表面涂层。目前的工作首次旨在将玉米蛋白-生物活性玻璃（BG）纳米复合材料浸涂在 AZ31B 镁合金上。合金表面还涂覆有天然玉米蛋白作为对照涂层。以十六烷基三甲基溴化铵（CTAB）为模板，通过仿生方法合成了玉米醇溶蛋白和 BG（zein_BG）复合材料所需的 BG 纳米颗粒。FTIR 证实了 BG 颗粒的形成，显示出特征 Si-O-Si 和 Si-O^–峰值。通过 TEM 报告平均直径为 6.67 ± 0.06 nm 的 BG 颗粒的纳米尺寸。SEM 显微照片显示镁合金表面成功沉积了玉米蛋白和 zein_BG 涂层。对浸入 HBSS 中的 zein_BG 涂层镁合金进行高分辨率 XPS 分析，结果显示腐蚀沉积有 Mg(OH) _2、 MgHPO ₄ .H ₂ O、CaHPO ₄ .H ₂ O、SiO _2、 MgCO ₃和 CaCO ₃在基材表面上。据报道，与裸露表面相比，玉米醇溶蛋白_BG 涂层的镁合金具有两倍以上的润湿性、95% 的粘附强度和 14 倍的表面粗糙度增加。对玉米蛋白和玉米蛋白_BG 涂层合金基材在 Hanks 平衡盐溶液 (HBSS) 中 37°C 10 天的重量损失测量表明，涂层后基材的重量损失急剧下降。结果表明，玉米蛋白_BG 涂层基材具有最大的防腐蚀功效（95.99%）。有趣的是，电化学测量表明，与未涂覆的基材（3.04 E ^-4 A.cm ^{-2 ）相比，zein_BG 涂覆的基材的腐蚀电流密度（2.41 E -6} A.cm ^-2 ）大幅降低）。电化学阻抗谱 (EIS) 证实了 zein_BG 涂层合金基底的电容行为。这些发现表明，简单的玉米蛋白_BG 复合浸涂涂层是一种成功的用于骨科应用的镁合金表面耐腐蚀植入涂层。