High-flow nasal cannula (HFNC) oxygen therapy, which is important in noninvasive respiratory support, is increasingly being used in critically ill neonates with respiratory failure because it is comfortable, easy to setup, and has a low incidence of nasal trauma. The advantages, indications, and risks of HFNC have been the focus of research in recent years, resulting in the development of the application. Based on current evidence, we developed guidelines for HFNC in neonates using the Grading of Recommendations Assessment, Development and Evaluation (GRADE). The guidelines were formulated after extensive consultations with neonatologists, respiratory therapists, nurse specialists, and evidence-based medicine experts. We have proposed 24 recommendations for 9 key questions. The guidelines aim to be a source of evidence and reference of HFNC oxygen therapy in clinical practice, and so that more neonates and their families will benefit from HFNC.

中文翻译：

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新生儿高流量鼻导管氧疗指南 (2022)

高流量鼻插管（HFNC）氧疗在无创呼吸支持中非常重要，由于舒适、易于设置且鼻部创伤发生率低，越来越多地用于呼吸衰竭的危重新生儿。HFNC的优点、适应症和风险一直是近年来研究的焦点，从而导致其应用的发展。根据现有证据，我们使用建议评估、制定和评估分级 (GRADE) 制定了新生儿 HFNC 指南。该指南是在与新生儿科医生、呼吸治疗师、护士专家和循证医学专家广泛协商后制定的。我们针对9个关键问题提出了24条建议。该指南旨在为HFNC氧疗在临床实践中提供证据和参考，让更多的新生儿及其家庭从HFNC中受益。