The efforts to use novel nanotechnologies in medicine and cancer have been widespread. In order to understand better the focus areas of cancer nanomedicine research to date, we conducted a survey of nanomedicine developmental and clinical research in conjunction with treatment of various cancers. The survey has been performed based on number of publications, rate of citations, entry into clinical trials, and funding rates by the National Cancer Institute. Our survey indicates that breast and brain cancers are the most and one of the least studied by nanotechnology researchers, respectively. Breast cancer nano-therapies seem to also be most likely to achieve clinical translation as the number of publications produced, amount of funding, total citations, and clinical trials (active and completed) are the highest when compared with research in other cancers. Brain cancer, despite its low survival, has capture much less attention of nanomedicine research community as survey indicated, although nanotechnology can offer novel approaches which can address brain cancer challenges.

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使用纳米药物治疗不同癌症的现状：趋势和观点

在医学和癌症领域使用新型纳米技术的努力已经很广泛。为了更好地了解迄今为止癌症纳米医学研究的重点领域，我们对与各种癌症治疗相结合的纳米医学开发和临床研究进行了调查。该调查是根据国家癌症研究所的出版物数量、引用率、临床试验参与情况和资助率进行的。我们的调查表明，乳腺癌和脑癌分别是纳米技术研究人员研究最多和最少的癌症之一。乳腺癌纳米疗法似乎也最有可能实现临床转化，因为与其他癌症的研究相比，其发表的出版物数量、资助金额、总引用次数和临床试验（正在进行的和已完成的）都是最高的。调查显示，尽管脑癌的生存率较低，但纳米医学研究界对脑癌的关注却少得多，尽管纳米技术可以提供解决脑癌挑战的新方法。