Insula is considered an important region of the brain in the generation and maintenance of a wide range of psychiatric symptoms, possibly due to being key in fundamental functions such as interoception and cognition in general. Investigating the possibility of targeting this area using non-invasive brain stimulation techniques can open new possibilities to probe the normal and abnormal functioning of the brain and potentially new treatment protocols to alleviate symptoms of different psychiatric disorders. In the current study, COMETS2, a MATLAB based toolbox was used to simulate the magnitude of the current density and electric field in the brain caused by different transcranial direct current stimulation (tDCS) protocols to find an optimum montage to target the insula and its 6 subregions for three different current intensities, namely 2, 3, and 4 mA. Frontal and occipital regions were found to be optimal candidate regions.. The results of the current study showed that it is viable to reach the insula and its individual subregions using tDCS.

岛叶被认为是大脑中产生和维持多种精神症状的重要区域，这可能是因为它是内感受和认知等基本功能的关键。研究使用非侵入性脑刺激技术针对该区域的可能性可以为探索大脑的正常和异常功能开辟新的可能性，并为减轻不同精神疾病的症状提供潜在的新治疗方案。在当前的研究中，COMETS2（一个基于 MATLAB 的工具箱）用于模拟不同经颅直流电刺激 (tDCS) 协议引起的大脑中电流密度和电场的大小，以找到针对脑岛及其 6 个区域的最佳蒙太奇。三个不同电流强度的子区域，即 2、3 和 4 mA。额叶和枕叶区域被认为是最佳候选区域。当前研究的结果表明，使用 tDCS 到达岛叶及其各个子区域是可行的。