Coccidiosis, also known as Eimeriosis, is a highly prevalent parasitic disease affecting sheep in nearly all sheep-rearing nations across the globe. Currently, there is a scarcity of literature documenting the specific lesions in sheep resulting from coccidia infection. This study aimed to investigate these characteristic lesions through necropsy, microscopic observation, and molecular biological techniques. As a result, Eimeria granulosa was identified as the causative agent, which induced distinct pathological alterations in the small intestine of lambs as observed during necropsy. Notably, E. granulosa manifested as small scattered petechiae and white spots, visible through the serous membrane of the small intestine, akin to the pathology observed in E. necatrix. Therefore, this study provides valuable insights for the accurate diagnosis of coccidiosis in sheep.

球虫病，也称为艾美球虫病，是一种非常流行的寄生虫病，影响全球几乎所有养羊国家的羊。目前，很少有文献记录球虫感染引起的羊的具体病变。本研究旨在通过尸检、显微镜观察和分子生物学技术来研究这些特征性病变。结果，颗粒艾美耳球虫被确定为病原体，在尸检过程中观察到，它引起了羔羊小肠的明显病理改变。值得注意的是，颗粒艾美耳球虫表现为分散的小瘀点和白点，透过小肠浆膜可见，类似于在恶毒艾美耳球虫中观察到的病理。因此，本研究为羊球虫病的准确诊断提供了有价值的见解。