The recent interest in increasing diversity in genetic research can be useful in uncovering novel insights into the genetic architecture of mental health disorders – globally and in previously unexplored settings such as low- and middle-income settings like Nigeria. Genetic research into mental health is potentially promising in Nigeria and we reflect on the challenges and opportunities for twin research which may be particularly suited to Nigeria. The higher rates of twinning in Africa and Nigeria specifically, make the twin design an affordable and readily maintainable approach for genetic research in the country. Despite potential challenges with recruitment, data collection, data analysis and dissemination; the success of current efforts suggest that the twin design can tapped even further for greater impact in the country. We highlight some ways in which the scope of twin research can be increased and suggest some ways in which existing challenges can be overcome including recent Patient Participant Involve and Engagement activities.

最近对增加遗传研究多样性的兴趣可能有助于揭示精神健康疾病遗传结构的新见解——无论是在全球范围内还是在以前未经探索的环境中，例如尼日利亚等低收入和中等收入环境中。心理健康的基因研究在尼日利亚具有潜在的前景，我们反思了双胞胎研究的挑战和机遇，这可能特别适合尼日利亚。特别是非洲和尼日利亚的双胞胎率较高，这使得双胞胎设计成为该国基因研究负担得起且易于维护的方法。尽管在招聘、数据收集、数据分析和传播方面存在潜在挑战；当前努力的成功表明，双胞胎设计可以进一步利用，在该国产生更大的影响。我们强调了一些可以扩大双胞胎研究范围的方法，并提出了一些可以克服现有挑战的方法，包括最近的患者参与者参与和参与活动。