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Mendelism: Connecting the Dots Across Centuries
Cytology and Genetics ( IF 0.5 ) Pub Date : 2023-09-25 , DOI: 10.3103/s0095452723050067
Nidhi Sukhija , K. K. Kanaka , P. B. Purohit , Indrajit Ganguly , Anoop Anand Malik , Sanjeev Singh , S. P. Dixit , Archana Verma , Aishwarya Dash

The year 2022 paid a bicentennial tribute to the phenomenal work of the father of Genetics, Gregor Johann Mendel for deciphering the genetic logic behind the phenotypes. His principles were distilled as the law of segregation and law of independent assortment. His work was rediscovered 34 yr later by H. De Vries, C. Correns, and E. Tschermak and popularized by W. Bateson. While C. Darwin accounted for similarities among organisms through the differences in the form of evolution, G. Mendel accounted for similarities through heredity; the ideological gaps were bridged mathematically by R. Fisher. Later with the test of time, the interaction among researchers paved Mendelian principles into different branches of genetics viz., cytogenetics, molecular genetics, population genetics, quantitative genetics, etc. At present we have landed in the era of genomics and the emerging field of phenomics which have potential to bridge the huge gap between demand and supply in different agro-industrial and allied goods. The need to connect the budding researchers in the field of genetics with Mendelism and its significance, catalyzed our concentrated effort to link Mendelism across the centuries, highlighting its importance and extrapolating the concept of heredity and variation from garden peas to different life forms. In conclusion, as our knowledge on genetics deepens, more insights on underlying mechanisms and subsequent applications will be witnessed.



中文翻译:

孟德尔主义:连接几个世纪的点点滴滴

2022 年是对遗传学之父格雷戈尔·约翰·孟德尔 (Gregor Johann Mendel) 破译表型背后遗传逻辑的杰出贡献的二百周年纪念。他的原则被提炼为隔离法则和独立分类法则。34 年后,他的作品被 H. De Vries、C. Correns 和 E. Tschermak 重新发现,并由 W. Bateson 推广。达尔文(C. Darwin)通过进化形式的差异解释了生物体之间的相似性,而孟德尔(G. Mendel)则通过遗传解释了生物体之间的相似性。R. Fisher 用数学方法弥合了意识形态的鸿沟。后来,经过时间的考验,研究人员之间的相互作用将孟德尔原理铺平到遗传学的不同分支,即细胞遗传学、分子遗传学、群体遗传学、数量遗传学等。目前,我们已经进入基因组学时代和新兴的表型组学领域,它们有潜力弥合不同农工业和相关产品的供需之间的巨大差距。将遗传学领域的崭露头角的研究人员与孟德尔主义及其重要性联系起来的需要,促使我们集中精力将几个世纪以来的孟德尔主义联系起来,强调其重要性,并推断从豌豆到不同生命形式的遗传和变异的概念。总之,随着我们对遗传学知识的加深,将会见证对潜在机制和后续应用的更多见解。将遗传学领域的崭露头角的研究人员与孟德尔主义及其重要性联系起来的需要,促使我们集中精力将几个世纪以来的孟德尔主义联系起来,强调其重要性,并推断从豌豆到不同生命形式的遗传和变异的概念。总之,随着我们对遗传学知识的加深,将会见证对潜在机制和后续应用的更多见解。将遗传学领域的崭露头角的研究人员与孟德尔主义及其重要性联系起来的需要,促使我们集中精力将几个世纪以来的孟德尔主义联系起来,强调其重要性,并推断从豌豆到不同生命形式的遗传和变异的概念。总之,随着我们对遗传学知识的加深,将会见证对潜在机制和后续应用的更多见解。

更新日期:2023-09-25
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