Since electrospinning can generate micro- to nanometre-scale fibres, it is widely used for fabricating wound dressings. Electrospun scaffolds with defined three-dimensional patterns at the mat surface can be efficiently fabricated using textured collectors that transfer the topography during the manufacturing process. However, the efficacy of surface pattern transfer from the collector to the mat, the correlation between the topography and the absorption capability and the effect of sterilisation on absorption have not yet been analysed. In this study, textured patterns were imprinted over polycaprolactone electrospun mats using textured collectors. The successful transferability of the patterns was quantified through height, hybrid and functional surface topography parameters. Additionally, ethylene oxide, hydrogen peroxide (H₂O₂) and ultraviolet (UV) sterilisation methods were tested, of which only UV preserved the morphological and functional integrity of the mat. Finally, fibroblasts were used to analyse the cytotoxicity and cellular response of the dressings, verifying their biocompatible nature. This study demonstrates that absorption capacity can be modulated by the surface texture of the wound dressing. The S _dq and S _dr parameters were identified as key surface characteristics for enhancing absorption capacity and yielded an increase of up to 176.76% compared with the non-textured control, thus revealing the potential of surface functionalisation for increasing exudate absorption.

中文翻译：

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为静电纺伤口敷料定制表面形貌以吸收渗出物

由于静电纺丝可以产生微米到纳米级的纤维，因此广泛用于制造伤口敷料。可以使用在制造过程中转移形貌的纹理收集器来有效地制造在垫子表面具有明确的三维图案的静电纺丝支架。然而，表面图案从收集器转移到垫子的功效、形貌与吸收能力之间的相关性以及灭菌对吸收的影响尚未分析。在这项研究中，使用纹理收集器将纹理图案压印在聚己内酯电纺垫上。通过高度、混合和功能表面形貌参数来量化图案的成功可转移性。此外，还测试了环氧乙烷、过氧化氢（H ₂ O ₂）和紫外线（UV）灭菌方法，其中只有紫外线保留了垫子的形态和功能完整性。最后，利用成纤维细胞分析敷料的细胞毒性和细胞反应，验证其生物相容性。这项研究表明，吸收能力可以通过伤口敷料的表面纹理来调节。 S _dq和S _dr参数被确定为增强吸收能力的关键表面特征，与无纹理对照相比，其增幅高达 176.76%，从而揭示了表面功能化在增加渗出液吸收方面的潜力。