Studies have reported conflicting results on the association between handgrip strength (HGS) and blood pressure during childhood and adolescence. High multicollinearity involving somatic components that influence both HGS and blood pressure might be an important source of bias. This study sought to investigate the independent effects of HGS and muscle mass on blood pressure levels in children and adolescents. Muscle mass and fat mass (Multifrequency Electrical Bioimpedance) and systolic (SBP) and diastolic (DBP) blood pressure (Automatic oscillometric device) were assessed in 833 volunteers aged 6–18 years, of both sexes. Handgrip strength-for-age quartiles were calculated and participants were assigned to groups by HGS quartiles. Analysis of covariance was conducted to address the linear association between HGS and SBP adjusted for height, muscle mass, and fat mass. To test for linear trend, contrast analysis was conducted. Partial eta-squared was used to confirm or rule out a small significant effect of the independent variables on SBP. The effect size of HGS on SBP was not significant in both sexes. In girls, 1.7% of the between-groups variance in SBP was accounted for by muscle mass (P = 0.016). In boys, 2.3% and 1.8% of the between-groups variance in SBP was accounted for by muscle mass (P = 0.001) and height (P = 0.005), respectively. In conclusion, children with a more advanced physical maturity for their age, that is, who are taller, stronger, and have greater fat-free mass, may be nearly reaching the physiological parameters of adulthood, and consequently have higher systolic blood pressure.

研究报告了关于儿童和青春期握力（HGS）与血压之间关系的相互矛盾的结果。涉及影响 HGS 和血压的体细胞成分的高度多重共线性可能是重要的偏差来源。本研究旨在调查 HGS 和肌肉质量对儿童和青少年血压水平的独立影响。对 833 名年龄 6-18 岁的男女志愿者进行了肌肉质量和脂肪质量（多频电生物阻抗）以及收缩压 (SBP) 和舒张压 (DBP) 血压（自动示波装置）的评估。计算握力与年龄的四分位数，并根据 HGS 四分位数将参与者分配到各组。进行协方差分析，以解决根据身高、肌肉质量和脂肪质量调整后的 HGS 和 SBP 之间的线性关联。为了测试线性趋势，进行了对比分析。部分 eta 平方用于确认或排除自变量对 SBP 的微小显着影响。HGS 对收缩压的影响大小在男女中均不显着。在女孩中，肌肉质量占组间收缩压差异的 1.7%（P  = 0.016）。在男孩中，肌肉质量 ( P  = 0.001) 和身高 ( P  = 0.005) 分别占组间收缩压差异的 2.3% 和 1.8% 。总之，与同龄人相比，身体成熟度更高的儿童，即更高、更强壮、去脂质量更大的儿童，可能接近成年期的生理参数，因此具有更高的收缩压。