Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders,Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

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Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration ( IF 2.8 ) Pub Date : 2024-01-23 , DOI: 10.1080/21678421.2023.2261979
Anna Matveeva _{1,

2} , Orla Watters _{2,

3} , Ani Rukhadze ₄ , Niraj Khemka _{1,

2} , Debora Gentile ₄ , Ivan Fernandez Perez _{1,

2} , Irene Llorente-Folch _{1,

2} , Cliona Farrell _{1,

2} , Elide Lo Cacciato ₄ , Joshua Jackson ₄ , Antonia Piazzesi ₄ , Lena Wischhof ₄ , Ina Woods _{1,

2} , Luise Halang _{1,

2} , Marion Hogg _{2,

3,

5} , Amaya Garcia Muñoz ₆ , Eugène T Dillon ₇ , David Matallanas ₆ , Ingrid Arijs _{8,

9} , Diether Lambrechts _{8,

9} , Daniele Bano ₄ , Niamh M C Connolly _{1,

2} , Jochen H M Prehn _{1,

2,

3}

Affiliation

Sporadic and familial amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disease that results in loss of motor neurons and, in some patients, associates with frontotempora...

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