Perinatal hypoxic–ischemic encephalopathy (HIE) is a condition that can lead to long-term cognitive, motor, and behavioral impairments in newborns. Although brain hypothermia therapy is currently the standard treatment for HIE, it does not provide complete neuroprotection. As a result, there is a need to explore additional therapies to enhance treatment outcomes. This study aims to investigate the potential role of Ginkgolide B (GB) in promoting neuroplasticity and facilitating spontaneous recovery after HIE.

中文翻译：

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银杏内酯 B 促进新生儿缺氧缺血性脑损伤后的自然恢复并增强内源性 Netrin-1

围产期缺氧缺血性脑病 (HIE) 是一种可导致新生儿长期认知、运动和行为障碍的疾病。尽管脑低温治疗是目前 HIE 的标准治疗方法，但它并不能提供完整的神经保护。因此，需要探索额外的疗法来提高治疗效果。本研究旨在探讨银杏内酯 B (GB) 在促进 HIE 后神经可塑性和促进自发恢复方面的潜在作用。