Objective: To investigate the current status and development trend of research on exosomes in cardiovascular disease (CVD) using bibliometric analysis and to elucidate trending research topics. Methods: Research articles on exosomes in CVD published up to April 2022 were retrieved from the Web of Science database. Data were organized using Microsoft Office Excel 2019. CiteSpace 6.1 and VOSviewer 1.6.18 were used for bibliometric analysis and result visualization. Results: Overall, 256 original research publications containing 190 fundamental research publications and 66 clinical research publications were included.

中文翻译：

---

外泌体在心血管疾病中的研究热点分析：基于文献计量学的文献综述

目的：通过文献计量分析探讨外泌体在心血管疾病（CVD）中的研究现状和发展趋势，阐明热点研究主题。方法：从 Web of Science 数据库中检索截至 2022 年 4 月发表的有关 CVD 外泌体的研究文章。使用 Microsoft Office Excel 2019 组织数据。使用 CiteSpace 6.1 和 VOSviewer 1.6.18 进行文献计量分析和结果可视化。结果：总体而言，纳入了 256 篇原始研究出版物，其中包括 190 篇基础研究出版物和 66 篇临床研究出版物。