Patches prepared from autologous, allogeneic, or xenogeneic tissues are widely used in the repair of congenital heart defects in children. Since 2002, cryopreserved allogeneic pericardial patches have been prepared in our institution as an alternative to commercially available patches. This study retrospectively reviewed donor and patient data concerning cryopreservation time and the clinical use of the pericardium in 382 children who were operated on at a single center between 2004 and 2021. There were 177 donors: 98 males and 79 females. The median donor age was 13 years (range: 1 month to 53 years) and the median cryopreservation time was 72 days (range: 3–685). There were 382 pediatric patients: 224 males and 158 females. The median patient age was 1 month (range: 3 days to 17.8 years). The patches were used for primary surgeries in 228 patients and for reoperations in 154. The patches were implanted into the right heart or venous circulation in 209 patients, the left heart or arterial circulation in 246 patients, and both sides of the circulatory system in 73. Extracardiac patch implantation was performed in 339 patients, intracardiac in 79 patients, and both intracardiac and extracardiac in 36 patients. Our study presents a single-center experience in the use of cryopreserved allogeneic pericardium. The pericardium can be used on the systemic and pulmonary sides of the circulatory system, in either extracardiac or intracardiac positions. However, there is no uniform strategy for selecting the “patch of choice” for correcting congenital heart defects in children, especially since there are few studies comparing several types of patches.

由自体、同种异体或异种组织制备的补片广泛用于修复儿童先天性心脏缺陷。自 2002 年以来，我们机构已制备冷冻保存的同种异体心包补片，作为市售补片的替代品。本研究回顾性回顾了 2004 年至 2021 年间在单一中心接受手术的 382 名儿童的心包冷冻保存时间和临床使用方面的供体和患者数据。共有 177 名供体：98 名男性和 79 名女性。捐赠者年龄中位数为 13 岁（范围：1 个月至 53 岁），冷冻保存时间中位数为 72 天（范围：3-685）。共有 382 名儿科患者：其中男性 224 名，女性 158 名。患者中位年龄为 1 个月（范围：3 天至 17.8 岁）。228 名患者使用该补片进行初次手术，154 名患者用于再次手术。209 名患者将补片植入右心或静脉循环，246 名患者植入左心或动脉循环，73 名患者植入两侧循环系统339 例患者进行了心外补片植入，79 例患者进行了心内补片植入，36 例患者同时进行了心内和心外植入。我们的研究展示了使用冷冻保存的同种异体心包的单中心经验。心包可用于循环系统的全身侧和肺侧，无论是心外还是心内位置。然而，对于选择“首选补片”来纠正儿童先天性心脏病并没有统一的策略，特别是因为很少有研究比较几种类型的补片。