Molecular docking and molecular dynamics simulations reveal the clinical resistance of the gatekeeper mutation V564F of FGFR2 against Infigratinib,Journal of Experimental Nanoscience

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Molecular docking and molecular dynamics simulations reveal the clinical resistance of the gatekeeper mutation V564F of FGFR2 against Infigratinib
Journal of Experimental Nanoscience ( IF 2.8 ) Pub Date : 2023-10-05 , DOI: 10.1080/17458080.2023.2264521
Guodong Zheng ₁ , Wuxia Liu ₁ , Qian Zhang ₂ , Tuo Shen ₃ , Jingfeng Zhang ₁ , Lei Jiang ₄ , Wenqi Liang ₄ , Bin Zhou ₄ , Ling Liu ₁ , Shenqian Xu ₁ , Minyu Li ₁

Affiliation

Fibroblast growth factor receptor 2 (FGFR2), as a transmembrane receptor tyrosine kinase, is implicated in a plethora of human cancers, including intrahepatic cholangiocarcinomas, breast cancers, a...

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