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Gender and Race-Related Disparities in the Management of Ventricular Arrhythmias
Trends in Cardiovascular Medicine ( IF 9.3 ) Pub Date : 2023-10-12 , DOI: 10.1016/j.tcm.2023.10.001
Mason Yoder 1 , Anthony Dils 1 , Apurba Chakrabarti 1 , Stefanie Driesenga 1 , Abiola Alaka 1 , Michael Ghannam 1 , Frank Bogun 1 , Jackson J Liang 1
Affiliation  

Modern studies have revealed gender and race-related disparities in the management and outcomes of cardiac arrhythmias, but few studies have focused on outcomes for ventricular arrhythmias (VAs) such as ventricular tachycardia (VT) or ventricular fibrillation (VF). The aim of this article is to review relevant studies and identify outcome differences in the management of VA among Black and female patients. We found that female patients typically present younger for VA, are more likely to have recurrent VA after catheter ablation, are less likely to be prescribed antiarrhythmic medication, and are less likely to receive primary prevention ICD placement as compared to male patients. Additionally, female patients appear to derive similar overall mortality benefit from primary prevention ICD placement as compared to male patients, but they may have an increased risk of acute post-procedural complications. We also found that Black patients presenting with VA are less likely to undergo catheter ablation, receive appropriate primary prevention ICD placement, and have significantly higher risk-adjusted 1-year mortality rates after hospital discharge as compared to White patients. Black female patients appear to have the worst outcomes out of any demographic subgroup.



中文翻译:

室性心律失常治疗中的性别和种族相关差异

现代研究揭示了心律失常的治疗和结果方面与性别和种族相关的差异,但很少有研究关注室性心律失常(VA)的结果,例如室性心动过速(VT)或心室颤动(VF)。本文的目的是回顾相关研究并确定黑人和女性患者 VA 管理的结果差异。我们发现,与男性患者相比,女性患者出现 VA 的时间通常较年轻,导管消融后更有可能复发 VA,不太可能服用抗心律失常药物,并且不太可能接受一级预防 ICD 放置。此外,与男性患者相比,女性患者似乎从一级预防 ICD 放置中获得了相似的总体死亡率获益,但她们发生急性术后并发症的风险可能增加。我们还发现,与白人患者相比,患有 VA 的黑人患者接受导管消融、接受适当的一级预防 ICD 放置的可能性较小,并且出院后风险调整后的 1 年死亡率显着较高。在所有人口亚组中,黑人女性患者的预后似乎最差。

更新日期:2023-10-12
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