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A sensory signature of unaffected biological parents predicts the risk of autism in their offspring
Psychiatry and Clinical Neurosciences ( IF 11.9 ) Pub Date : 2023-10-08 , DOI: 10.1111/pcn.13605
Chenyi Chen, Yawei Cheng, Chien-Te Wu, Chung-Hsin Chiang, Ching-Ching Wong, Chih-Mao Huang, Róger Marcelo Martínez, Ovid J. L. Tzeng, Yang-Teng Fan

Despite the emphasis on sensory dysfunction phenotypes in the revised diagnostic criteria for autism spectrum disorder (ASD), there has been limited research, particularly in the field of neurobiology, investigating the concordance in sensory features between individuals with ASD and their genetic relatives. Therefore, our objective was to examine whether neurobehavioral sensory patterns could serve as endophenotypic markers for ASD.

中文翻译:

未受影响的亲生父母的感官特征可以预测其后代患自闭症的风险

尽管在修订后的自闭症谱系障碍 (ASD) 诊断标准中强调了感觉功能障碍表型,但对自闭症谱系障碍 (ASD) 患者与其遗传亲属之间感觉特征一致性的研究却很有限,特别是在神经生物学领域。因此,我们的目标是检查神经行为感觉模式是否可以作为自闭症谱系障碍的内表型标记。
更新日期:2023-10-08
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