Background: Breast carcinoma (BC) threatens the physical and mental health of women worldwide, and early diagnosis is important for improving patient outcomes and ensuring successful treatment.
Purpose: This research mainly aims to compare and analyze the value of molybdenum target X-ray and high-frequency color Doppler flow imaging (CDFI) in the early diagnosis of BC.
Methods: First, 102 patients with suspected early-stage BC (ESBC) admitted to Henan Provincial People’s Hospital were examined by molybdenum target X-ray and CDFI. Based on the pathological findings, the diagnostic efficiency data of the two diagnostic modalities such as positive detection rate (PDR), positive predictive value (PPV), negative predictive value (NPV), sensitivity (SEN), specificity (SPE), and accuracy (ACC), as well as imaging information like masses, microcalcifications (MCs), axillary lymph node (LN) metastases, and blood flow signal or vascular sign abnormalities were analyzed.
Results: CDFI contributed to higher PDR, PRV, NPV, SEN, and ACC than molybdenum target X-ray in ESBC diagnosis, but similar SPE. The combined diagnosis of molybdenum target X-ray plus CDFI contributed to even higher PDR, PRV, NPV, SEN, and ACC than molybdenum target X-ray alone and higher ACC than CDFI. Imaging inspection revealed that the number of cases of masses, axillary LN metastases, and abnormalities in blood flow signals or vascular signs detected by CDFI was significantly higher than that by molybdenum target X-ray, while the number of MCs was significantly lower.
Conclusion: Molybdenum target X-ray plus CDFI is more effective in the diagnosis of ESBC and plays a complementary role in imaging examination, which can synergistically improve the diagnostic ACC of ESBC and is worthy of clinical promotion.



中文翻译：

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钼靶X线与高频彩色多普勒超声在乳腺癌早期诊断中的价值对比分析

背景：乳腺癌（BC）威胁着全世界女性的身心健康，早期诊断对于改善患者预后和确保成功治疗非常重要。
目的：本研究主要旨在对比分析钼靶X线与高频彩色多普勒血流成像（CDFI）在BC早期诊断中的价值。
方法：首先对河南省人民医院收治的102例疑似早期BC（ESBC）患者进行钼靶X线和CDFI检查。根据病理结果，两种诊断方式的诊断效率数据，如阳性检出率（PDR）、阳性预测值（PPV）、阴性预测值（NPV）、敏感性（SEN）、特异性（SPE）和准确性(ACC) 以及肿块、微钙化 (MC)、腋窝淋巴结 (LN) 转移、血流信号或血管征异常等影像信息进行了分析。
结果：在 ESBC 诊断中，CDFI 比钼靶 X 线具有更高的 PDR、PRV、NPV、SEN 和 ACC，但与 SPE 相似。钼靶X射线联合CDFI的联合诊断比单独钼靶X射线具有更高的PDR、PRV、NPV、SEN和ACC，并且比CDFI更高的ACC。影像学检查发现，CDFI检测到的肿块、腋窝淋巴结转移、血流信号或血管征异常的例数明显高于钼靶X线，而MC的数量明显较少。
结论:钼靶X线联合CDFI对ESBC的诊断更为有效,且与影像学检查具有互补作用,可协同提高ESBC的诊断ACC,值得临床推广。