The current study compared the reliability of manual collateral sulcus depth and entorhinal and transentorhinal cortical volume measurements between native oriented MRI scans versus MRI scans realigned to the hippocampal long axis. Data included 10 participants with two serial 3.0T MRI scans from the Alzheimer's Disease Neuroimaging Initiative. Both collateral sulcus depth and entorhinal and transentorhinal cortical volume measurement reliability improved from the native to the hippocampal oriented scans. Standardizing scan orientation is important to optimize reliability of MRI-derived manual measurements of the entorhinal and transentorhinal cortices. In quantitative MRI studies, aligning scans to a common, normalized orientation is recommended.

目前的研究比较了自然定向 MRI 扫描与重新对准海马长轴的 MRI 扫描之间手动侧副沟深度以及内嗅和经内嗅皮质体积测量的可靠性。数据包括来自阿尔茨海默病神经影像计划的 10 名参与者进行的两次连续 3.0T MRI 扫描。从原生扫描到海马定向扫描，侧副沟深度以及内嗅和经内嗅皮质体积测量的可靠性均得到提高。标准化扫描方向对于优化 MRI 衍生的内嗅和经内嗅皮质手动测量的可靠性非常重要。在定量 MRI 研究中，建议将扫描对齐到共同的标准化方向。