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Challenges and Solutions in the Recombinant Expression of Membrane Proteins
Protein & Peptide Letters ( IF 1.6 ) Pub Date : 2023-10-10 , DOI: 10.2174/0109298665264728230920070145
Caijuan Liu 1 , Hanxue He 1 , Jie Tian 1 , Yunqi Ma 1
Affiliation  

Membrane proteins are important components of the proteome and play key roles in many biological processes, such as signal transduction, material transport, cell recognition, etc. Membrane proteins are involved in several fields, and more and more researchers want to understand them. However, the structural properties of membrane proteins make their recombinant expression yield low. This adversely affects the study of the structure and function of membrane proteins. Therefore, it is crucial to have a comprehensive and up-to-date understanding of membrane protein recombinant expression. Based on the current stage of research on membrane proteins, the article describes the current challenges faced by membrane protein recombinant expression and the solutions that can be applied to lay the foundation for a better study of membrane proteins in the future.

中文翻译:

膜蛋白重组表达的挑战与解决方案

膜蛋白是蛋白质组的重要组成部分,在许多生物过程中发挥着关键作用,如信号转导、物质运输、细胞识别等。膜蛋白涉及多个领域,越来越多的研究人员希望了解它们。然而,膜蛋白的结构特性使其重组表达率较低。这对膜蛋白的结构和功能的研究产生不利影响。因此,对膜蛋白重组表达有全面和最新的了解至关重要。文章结合现阶段膜蛋白研究现状,阐述了目前膜蛋白重组表达面临的挑战以及可应用的解决方案,为今后更好地研究膜蛋白奠定基础。
更新日期:2023-10-10
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