Words would only be sounds, if they did not activate phonemic and semantic operations in separate cortical regions, and their serial occurrence would remain incomprehensible without integration into a suitable syntactic frame. Coming from this simple notion, two components of biolinguistic processing seem principally relevant, first, the flexible binding of distributed cortical areas to recruit the material for meaningful messages and, second, the structuring of this material according to habitual language features. Based on studies in patients with deep-brain stimulation (DBS) for the treatment of neurological movement disorders, we propose that thalamic nuclei contribute to the former operation, whereas the basal ganglia rather support the latter aspect of language processing. The current review summarizes DBS-dependent task performances and neurophysiological recordings from thalamic and basal ganglia DBS that target nuclei underlying this view.

如果单词没有在不同的皮质区域激活音素和语义操作，那么它们就只能是声音，并且如果不整合到合适的句法框架中，它们的连续出现将仍然难以理解。从这个简单的概念来看，生物语言处理的两个组成部分似乎主要相关，首先，分布式皮质区域的灵活结合，以招募有意义的信息的材料，其次，根据习惯的语言特征构建该材料。基于对深部脑刺激（DBS）治疗神经运动障碍患者的研究，我们提出丘脑核团有助于前一操作，而基底神经节则支持后一语言处理方面。当前的综述总结了 DBS 依赖性任务表现以及来自丘脑和基底神经节 DBS 的神经生理学记录，这些记录以这一观点为基础。