Although our understanding of lung cancer has significantly improved in the past decade, it is still a disease with a high incidence and mortality rate. The key reason is that the efficacy of the therapeutic drugs is limited, mainly due to insufficient doses of drugs delivered to the lungs. To achieve precise lung cancer diagnosis and treatment, nano-particles (NPs) pulmonary delivery techniques have attracted much attention and facilitate the exploration of the potential of those in inhalable NPs targeting tumor lesions. Since the therapeutic research focusing on pulmonary delivery NPs has rapidly developed and evolved substantially, this review will mainly discuss the current developments of pulmonary delivery NPs for precision lung cancer diagnosis and therapy.

中文翻译：

---

用于肺癌诊断和治疗的纳米颗粒肺部输送：最新进展和未来前景

尽管过去十年我们对肺癌的认识有了显着提高，但它仍然是一种发病率和死亡率较高的疾病。关键原因是治疗药物的功效有限，主要是输送到肺部的药物剂量不足。为了实现肺癌的精准诊断和治疗，纳米颗粒（NPs）肺部输送技术引起了广泛关注，并促进了可吸入纳米颗粒针对肿瘤病灶的潜力的探索。由于以肺递送纳米粒子为重点的治疗研究已经迅速发展并取得了长足的发展，本文将主要讨论肺递送纳米粒子在肺癌精准诊断和治疗中的最新进展。