Various therapeutic methods are employed to facilitate the clearance of secretions accumulated in the respiratory tracts of individuals with lower respiratory tract disorders. High-frequency chest wall oscillation (HFCWO) device, designed to apply variable amplitude and frequency vibrations to the individuals' chests, stands out among these therapies. In this study, the effectiveness of this treatment method was investigated numerically using computational fluid dynamics (CFD) on the generated mucus-obstructed bronchial geometry. The conducted analyses compared the effects of vibrations acting in the axial, radial, and tangential directions on the clearance of mucus, which exhibits non-Newtonian flow behavior with shear-thinning properties. Simultaneously, the effects of changes in vibration amplitude and frequency, pressure differentials, fluid properties, and ciliary movements on the flow were separately examined and interpreted. The findings demonstrate that ciliary movements are insufficient in mucus-accumulated airways, applied vibrations enhance mucus clearance, and potential improvements in flow are quite sensitive to boundary conditions.

采用多种治疗方法来促进患有下呼吸​​道疾病的个体清除呼吸道中积聚的分泌物。高频胸壁振荡 (HFCWO) 装置在这些疗法中脱颖而出，旨在对个人胸部施加可变幅度和频率的振动。在这项研究中，使用计算流体动力学（CFD）对生成的粘液阻塞的支气管几何形状进行数值研究，研究了这种治疗方法的有效性。进行的分析比较了轴向、径向和切向方向的振动对粘液间隙的影响，粘液表现出具有剪切稀化特性的非牛顿流动行为。同时，分别检查和解释了振动幅度和频率、压差、流体性质和纤毛运动变化对血流的影响。研究结果表明，粘液积聚的气道中纤毛运动不足，施加的振动增强了粘液清除能力，并且流量的潜在改善对边界条件非常敏感。