An important factor contributing to the low rate of success in identifying effective therapies for brain tumor patients is the slow, inefficient, and expensive process of drug development, as well as small patient numbers, low patient participation in clinical trials, and reluctance of patients to enroll in ineffective control arms. In recent years, a number of novel trial designs have been developed to try to address some of these issues.

中文翻译：

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神经肿瘤学的新颖试验设计。

导致脑肿瘤患者有效治疗方法成功率低的一个重要因素是药物开发过程缓慢、低效且昂贵，以及患者数量少、患者参与临床试验的程度低以及患者不愿意接受治疗。加入无效的控制部门。近年来，已经开发了许多新颖的试验设计来尝试解决其中一些问题。