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Remote Ischemic conditioning as an emerging tool to improve corticospinal transmission in individuals with chronic spinal cord injury.
Current Opinion in Neurology ( IF 4.8 ) Pub Date : 2023-10-02 , DOI: 10.1097/wco.0000000000001216
Yu-Kuang Wu 1, 2 , Jill M Wecht 1, 2 , Ona E Bloom 2, 3, 4 , Gino S Panza 5, 6 , Noam Y Harel 1, 2
Affiliation  

Remote ischemic conditioning (RIC) involves transient blood flow restriction to one limb leading to systemic tissue-protective effects. RIC shares some potential underlying mechanisms with intermittent hypoxia (IH), in which brief bouts of systemic hypoxia trigger increases in growth factor expression and neural plasticity. RIC has shown promise in acute myocardial infarction and stroke but may be applicable toward chronic neuropathology as well. Consequently, this review discusses similarities and differences between RIC and IH and presents preliminary and ongoing research findings regarding RIC.

中文翻译:

远程缺血调理作为一种新兴工具,可改善慢性脊髓损伤患者的皮质脊髓传递。

远程缺血调节(RIC)涉及对一侧肢体的短暂血流限制,从而产生全身组织保护作用。RIC 与间歇性缺氧 (IH) 具有一些潜在的潜在机制,即短暂的全身缺氧会触发生长因子表达和神经可塑性增加。RIC 在急性心肌梗死和中风方面已显示出前景,但也可能适用于慢性神经病理学。因此,本综述讨论了 RIC 和 IH 之间的异同,并介绍了有关 RIC 的初步和正在进行的研究结果。
更新日期:2023-10-02
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