Defining the commonalities between post-transcriptional and post-translational modification communities,Trends in Biochemical Sciences

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Defining the commonalities between post-transcriptional and post-translational modification communities
Trends in Biochemical Sciences ( IF 13.8 ) Pub Date : 2023-10-24 , DOI: 10.1016/j.tibs.2023.09.011
Zachary T Baumer ₁ , Luke Erber ₂ , Elizabeth Jolley ₃ , Sheldon Lawrence ₄ , Chuwei Lin ₅ , Shino Murakami ₆ , Veronica Perez ₇ , Wil Prall ₈ , Cassandra Schaening-Burgos ₉ , Megan Sylvia ₁₀ , Sixue Chen ₁₁ , Brian D Gregory ₈

Affiliation

Department of Chemical and Biological Engineering, University of Colorado, Boulder, CO 80305, USA.
Department of Medicinal Chemistry, University of Kansas, Lawrence, KS 66044, USA.
Department of Chemistry, Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.
Department of Biology, Oxford College of Emory University, Oxford, GA 30054, USA.
Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.
Department of Pharmacology, Weill Cornell Medicine, Cornell University, New York, NY 10065, USA.
Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA.
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Remix Therapeutics, Watertown, MA 02472, USA.
Intercollege Graduate Degree Program in Plant Biology, Department of Biology, and Department of Chemistry, Pennsylvania State University, University Park, PA 16802, USA.
Department of Biology, University of Mississippi, University, MS 38677, USA.

Post-transcriptional modifications of RNA (PRMs) and post-translational modifications of proteins (PTMs) are important regulatory mechanisms in biological processes and have many commonalities. However, the integration of these research areas is lacking. A recent discussion identified the priorities, areas of emphasis, and necessary technologies to advance and integrate these areas of study.

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