Mixed depression is a common mental health problem that causes great distress to the patient’s life and social functioning. Due to historical and cultural tourism having communicative characteristics, it may have a positive effect on improving the symptoms of depression and is considered to affect improving mixed depression.

A randomized controlled trial design was used in this study, which included 100 patients with mixed depression. The intervention group received an 8-week historical and cultural tourism intervention, while the control group continued to receive conventional psychotherapy. The analysis tool uses SPSS23.0.

At the end of the study, patients in the intervention group showed significant improvement in depressive symptoms as measured by the Hamilton Depression Scale and Quality of Life questionnaire. Depression symptoms were reduced by 30 % in the intervention group compared to the control group. In addition, life quality in the intervention group also improved significantly, by 20% compared to the control group.

Historical and cultural tourism has a positive effect on improving the symptoms and life quality of patients with mixed depression. By providing new sensory and cognitive experiences, historical and cultural tourism can divert patients’ attention and emotions, and alleviate their depressive symptoms. The combination of historical and cultural tourism with drug and psychotherapy can become an effective and feasible treatment method, which provides a new choice and treatment means for patients with mixed depression.

混合抑郁症是一种常见的心理健康问题，给患者的生活和社会功能造成巨大困扰。由于历史文化旅游具有交际特征，可能对改善抑郁症症状有积极作用，被认为对改善混合型抑郁症有影响。

本研究采用随机对照试验设计，纳入 100 名混合抑郁症患者。干预组接受为期8周的历史文化旅游干预，对照组继续接受常规心理治疗。分析工具采用SPSS23.0。

研究结束时，通过汉密尔顿抑郁量表和生活质量问卷测量，干预组患者的抑郁症状显着改善。与对照组相比，干预组的抑郁症状减少了 30%。此外，干预组的生活质量也显着改善，比对照组提高了20%。

历史文化旅游对改善混合抑郁症患者的症状和生活质量具有积极作用。历史文化旅游通过提供新的感官和认知体验，可以转移患者的注意力和情绪，缓解患者的抑郁症状。历史文化旅游与药物、心理治疗相结合，可以成为一种有效可行的治疗方法，为混合型抑郁症患者提供了新的选择和治疗手段。