Hemochromatosis is a genetic disorder characterized by excessive absorption and accumulation of iron in the body. It is one of the most common inherited disorders. The excess iron deposition can cause damage to various organs, including the liver, heart, pancreas, and joints. If left untreated, hemochromatosis can lead to serious complications such as cirrhosis, diabetes, heart failure, and increased risk of certain cancers. Iron overload in hemochromatosis significantly affects the cardiovascular system, leading to morbidity and mortality. This article reviews the current literature describing the pathogenesis and various cardiovascular manifestations of hemochromatosis, including dilated cardiomyopathy, conduction abnormalities, heart failure, cardiac fibrosis, myocardial infarction, and valvular heart disease. This article aims to provide a detailed understanding of the cardiovascular manifestations associated with hemochromatosis and their underlying mechanisms through a review of current literature in publicly available databases.

中文翻译：

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血色素沉着症的心血管表现：病理生理学、机制和治疗方案的回顾。

血色素沉着症是一种遗传性疾病，其特征是体内铁的过度吸收和积累。它是最常见的遗传性疾病之一。过量的铁沉积会对多种器官造成损害，包括肝脏、心脏、胰腺和关节。如果不及时治疗，血色素沉着症会导致严重的并发症，如肝硬化、糖尿病、心力衰竭，并增加患某些癌症的风险。血色素沉着病中的铁超载会显着影响心血管系统，导致发病率和死亡率。本文回顾了目前描述血色素沉着病发病机制和各种心血管表现的文献，包括扩张型心肌病、传导异常、心力衰竭、心脏纤维化、心肌梗死和瓣膜性心脏病。本文旨在通过回顾公开数据库中的当前文献，详细了解与血色素沉着症相关的心血管表现及其潜在机制。