Purpose: Prostate cancer and its treatment may affect patients’ sexual function and social wellbeing. This study investigated the relationship between social/family wellbeing and sexual health in patients with prostate cancer. Additionally, the moderating effect of clinical characteristics on this relationship was also explored.
Patients and Methods: This is a descriptive correlational study using baseline data of a longitudinal study enrolling 137 patients with prostate cancer. Sexual Function (SF) and Sexual Function Distress (SFD) data were collected using the Symptom Index questionnaire. Demographic data were obtained during study intake and clinical data were obtained from chart review. Bivariate correlation determined the correlations among continuous demographic/clinical data, social/family wellbeing, and sexual health. Moderated regression analysis determined the moderating effects of clinical characteristics on the relationship of social/family wellbeing and sexual health.
Results: Moderate positive correlation was found between social/family wellbeing and SF, whereas a weak negative correlation was noted between social/family wellbeing and SFD. Depression was significantly correlated with social/family wellbeing and SFD. Both sexual health domains were significantly correlated with Gleason score. A significant difference was noted in the social/family wellbeing and both SF and SFD in participants receiving androgen deprivation therapy (ADT) compared to those not receiving ADT. Concomitant ADT use was the only clinical characteristic found to be a significant moderator of the relationship between social/family wellbeing and SFD, but none of the clinical characteristics was found to have a moderating effect on the relationship of social/family wellbeing and SF. Among patients who were not receiving ADT, high social/family wellbeing was associated with low SFD. Patients who were receiving ADT reported slightly higher SFD despite having higher social/family wellbeing.
Conclusion: Ensuring sexual health in patients with prostate cancer requires a comprehensive approach to address factors contributing to sexual health such as side effects of treatment and family wellbeing.

Keywords: sexual function, sexual function distress, family health, male reproductive health


中文翻译：

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接受前列腺癌治疗的患者的家庭福祉和性健康

目的：前列腺癌及其治疗可能会影响患者的性功能和社会福祉。这项研究调查了前列腺癌患者的社会/家庭福祉与性健康之间的关系。此外，还探讨了临床特征对这种关系的调节作用。
患者和方法：这是一项描述性相关研究，使用了一项纳入 137 名前列腺癌患者的纵向研究的基线数据。使用症状指数问卷收集性功能（SF）和性功能困扰（SFD）数据。人口统计数据是在研究期间获得的，临床数据是从图表审查中获得的。双变量相关性确定了连续人口统计/临床数据、社会/家庭福祉和性健康之间的相关性。调节回归分析确定了临床特征对社会/家庭福祉和性健康关系的调节作用。
结果：社会/家庭幸福感与 SF 之间呈中度正相关，而社会/家庭幸福感与 SFD 之间呈弱负相关。抑郁症与社会/家庭幸福感和 SFD 显着相关。两个性健康领域都与格里森评分显着相关。与未接受雄激素剥夺疗法 (ADT) 的参与者相比，接受雄激素剥夺疗法 (ADT) 的参与者在社会/家庭福祉以及 SF 和 SFD 方面存在显着差异。伴随 ADT 的使用是唯一被发现对社会/家庭幸福感与 SFD 之间关系具有显着调节作用的临床特征，但没有发现任何临床特征对社会/家庭幸福感与 SF 之间的关系具有调节作用。在未接受 ADT 的患者中，较高的社会/家庭幸福感与较低的 SFD 相关。尽管社会/家庭幸福感较高，但接受 ADT 的患者报告 SFD 略高。
结论：确保前列腺癌患者的性健康需要采取综合方法来解决影响性健康的因素，例如治疗的副作用和家庭福祉。

关键词：性功能、性功能困扰、家庭健康、男性生殖健康