Tissue engineering and drug delivery have emerged as promising fields that hold the potential to revolutionize modern healthcare. The widespread use of synthetic polymers in these applications raises concerns about their environmental impact and biocompatibility. In response, researchers have shifted their focus toward the development of eco-friendly biopolymers as viable alternatives. This review paper aims to comprehensively analyze the progress made in the utilization of biopolymers for tissue engineering and drug delivery, with an emphasis on their ecological advantages and biomedical performance. The review begins by exploring the diverse sources of biopolymers, such as proteins, polysaccharides, and nucleic acids, derived from renewable resources, agricultural waste, etc. The discussion then delves into the unique properties of these biopolymers, including their biodegradability, nontoxic nature, and potential for controlled drug release. The incorporation of biopolymers in tissue engineering scaffolds is critically examined. The review also explores the role of biopolymers in the drug delivery systems, with a focus on nanoparticles, microparticles, hydrogels, and films. The capability of biopolymers to encapsulate and protect therapeutic agents, as well as their controlled release, is discussed in the context of targeted drug delivery and improved therapeutic outcomes. This paper highlights the challenges and future perspectives in the field of eco-friendly biopolymers for tissue engineering and drug delivery. Promising advancements in biofabrication techniques, nanotechnology, and personalized medicine are identified as key drivers for the rapid translation of these materials into the clinical applications. The development of eco-friendly biopolymers offers a sustainable and bio-safe alternative to the traditional synthetic polymers in tissue engineering and drug delivery. This comprehensive review underscores the crucial role of biopolymers in fostering advancements in regenerative medicine and therapeutic interventions while prioritizing environmental preservation and human health.

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用于组织工程和药物输送的环保生物聚合物的开发

组织工程和药物输送已成为有前景的领域，有可能彻底改变现代医疗保健。合成聚合物在这些应用中的广泛使用引起了人们对其环境影响和生物相容性的担忧。作为回应，研究人员已将重点转向开发环保生物聚合物作为可行的替代品。本文旨在全面分析生物聚合物在组织工程和药物输送方面的应用进展，重点关注其生态优势和生物医学性能。该综述首先探讨了生物聚合物的多种来源，例如源自可再生资源、农业废物等的蛋白质、多糖和核酸。然后讨论深入研究了这些生物聚合物的独特性质，包括其生物降解性、无毒性质、和受控药物释放的潜力。生物聚合物在组织工程支架中的掺入受到严格检查。该综述还探讨了生物聚合物在药物输送系统中的作用，重点关注纳米颗粒、微粒、水凝胶和薄膜。在靶向药物递送和改善治疗结果的背景下讨论了生物聚合物封装和保护治疗剂及其控制释放的能力。本文重点介绍了用于组织工程和药物输送的环保生物聚合物领域面临的挑战和未来前景。生物制造技术、纳米技术和个性化医疗方面的有前景的进步被认为是这些材料快速转化为临床应用的关键驱动力。环保生物聚合物的开发为组织工程和药物输送中的传统合成聚合物提供了可持续且生物安全的替代品。这篇全面的综述强调了生物聚合物在促进再生医学和治疗干预方面的进步，同时优先考虑环境保护和人类健康方面的关键作用。