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GeogRaphic and socioecoNomic Distribution of real-world Indian data of home blood pressure monitoring (GRAND Study): Study protocol for an observational study in 18 medical centers across India
Journal of Clinical Hypertension ( IF 2.8 ) Pub Date : 2023-11-01 , DOI: 10.1111/jch.14713
Narsingh Verma 1 , Noriko Matsushita 2 , Ebtehal Salman 3 , Takayoshi Ohkubo 4 , Yutaka Imai 5
Affiliation  

One-fourth of death in India is attributed to cardiovascular disease (CVD) and more than 80% is related to ischemic heart disease and stroke. The main risk factor for CVD is hypertension. Every third person in India suffers from hypertension and the prevalence increased drastically in the past 20 years, especially among the youngest age group of 20 and 44 years. Regardless of being under anti-hypertension medication, the blood pressure (BP) control rate in the country is still low ranging between 6% and 28% only. Assessing the “true BP control rate” should be performed using both clinic BP measurement and out-of-office BP measurement as the latter shows better prognosis for patients’ hypertension and CVD outcomes. Home blood pressure monitoring (HBPM) shows superiority over ambulatory BP measurement as multiple measurements can be collected at the patient's convenience. Only limited evidence on HBPM in India is available and it's either lacking in hypertension participants or of a small sample size. This study will investigate the real BP control status among 2000 hypertensive patients from 18 centers in 12 states across Pan-India. The outcome of this study will emphasize the value of establishing BP control management practice guidelines suitable for physicians and help policymakers in building proper strategies for hypertension management to reduce the CVD burden on the health situation in India.

中文翻译:

印度家庭血压监测真实数据的地理和社会经济分布(大研究):印度 18 个医疗中心观察性研究的研究方案

印度四分之一的死亡归因于心血管疾病 (CVD),其中超过 80% 与缺血性心脏病和中风有关。CVD的主要危险因素是高血压。印度三分之一的人患有高血压,且患病率在过去 20 年急剧增加,特别是在 20 岁和 44 岁的最年轻年龄组中。尽管接受抗高血压药物治疗,但该国的血压控制率仍然较低,仅在6%至28%之间。应使用诊所血压测量和诊室外血压测量来评估“真实血压控制率”,因为后者对患者高血压和心血管疾病的预后显示出更好的预后。家庭血压监测 (HBPM) 优于动态血压测量,因为可以在患者方便的时候收集多次测量结果。印度关于 HBPM 的证据有限,要么缺乏高血压参与者,要么样本量较小。本研究将调查全印度 12 个邦 18 个中心的 2000 名高血压患者的真实血压控制状况。这项研究的结果将强调建立适合医生的血压控制管理实践指南的价值,并帮助政策制定者制定适当的高血压管理策略,以减轻心血管疾病对印度健康状况的负担。
更新日期:2023-11-01
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