Combination therapy of niclosamide with gemcitabine inhibited cell proliferation and apoptosis via Wnt/β-catenin/c-Myc signaling pathway by inducing β-catenin ubiquitination in pancreatic cancer,Cancer Biology & Therapy

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Combination therapy of niclosamide with gemcitabine inhibited cell proliferation and apoptosis via Wnt/β-catenin/c-Myc signaling pathway by inducing β-catenin ubiquitination in pancreatic cancer
Cancer Biology & Therapy ( IF 3.6 ) Pub Date : 2023-11-02 , DOI: 10.1080/15384047.2023.2272334
Hyeon Woong Kang _{1,

2} , Ju Hyun Kim ₃ , Da Eun Lee ₁ , Yun Sun Lee ₁ , Myeong Jin Kim _{1,

2} , Hyung Sun Kim ₁ , SungSoon Fang _{2,

3} , Bo Eun Lee _{4,

5} , Kyung Jin Lee _{4,

5} , Jongman Yoo _{4,

5} , Hyo Jung Kim ₁ , Joon Seong Park ₁

Affiliation

Pancreatic ductal adenocarcinoma (PDAC) is a type of cancer with high morbidity and mortality rates worldwide. Owing to a lack of therapeutic options, the overall survival rate of patients with pan...

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