The application of nanopore targeted sequencing for pathogen diagnosis in bronchoalveolar lavage fluid of patients with pneumonia: a prospective multicenter study,Infectious Diseases

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The application of nanopore targeted sequencing for pathogen diagnosis in bronchoalveolar lavage fluid of patients with pneumonia: a prospective multicenter study
Infectious Diseases ( IF 5.8 ) Pub Date : 2023-12-18 , DOI: 10.1080/23744235.2023.2276785
Qinqing Lin _{1,

2} , Yake Yao ₁ , Xi Li ₃ , Shanshan Zhang _{1,

4} , Huimin Guo _{5,

6} , Xiaolong Ma ₇ , Wenyu Chen ₆ , Chuhui Ru ₈ , Limin Wang ₉ , Bin Wang ₁₀ , Qiang Ma ₁₁ , Junfei Zhu ₁₂ , Xuemei Lin ₁₃ , Qi Chen _{5,

6} , Hui Lou ₁ , Qi Chen ₁ , Junjun Chen ₁ , Zhu Zeng ₁ , Jianying Zhou ₁ , Yan Chen ₁₄ , Yunsong Yu ₁₄ , Hua Zhou ₁

Affiliation

Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Department of Critical Care Medicine, Affiliated Hospital of Shaoxing University, Shaoxing, China.
Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Department of Respiratory and Critical Care Medicine, Beilun People's Hospital, Ningbo, China.
Zhejiang Digena Diagnosis Technology CO., Ltd., Hangzhou, Zhejiang, China.
Key Laboratory of Digital Technology in Medical Diagnostics of Zhejiang Province, Dian Diagnostics Group Co., Ltd., Hangzhou, Zhejiang, China.
Department of Respiratory and Critical Care Medicine, The First Hospital of JiaXing, JiaXing, China.
Department of Respiratory and Critical Care Medicine, Red Cross Society Hospital of Hangzhou, Hangzhou, China.
Department of Respiratory and Critical Care Medicine, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Department of Respiratory and Critical Care Medicine, Huzhou Central Hospital, Huzhou, China.
Department of Respiratory and Critical Care Medicine, The Second People's Hospital of Yuhang District, Hangzhou, China.
Department of Respiratory and Critical Care Medicine, Taizhou Central Hospital, Taizhou, China.
Department of Respiratory and Critical Care Medicine, Jiangshan People's Hospital, Quzhou, China.
Department of Infectious Disease, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

To evaluate the value of nanopore targeted sequencing in diagnosing pneumonia pathogens.This large-scale multicentre prospective study performed in 8 hospitals across China from April to October 20...

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