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Design of experiment (DoE) as a quality by design (QbD) tool to optimise formulations of lipid nanoparticles for nose-to-brain drug delivery
Expert Opinion on Drug Delivery ( IF 6.6 ) Pub Date : 2023-12-29 , DOI: 10.1080/17425247.2023.2274902
A C Correia 1, 2 , J N Moreira 3, 4 , J M Sousa Lobo 1, 2 , A C Silva 1, 2, 5
Affiliation  

The nose-to-brain route has been widely investigated to improve drug targeting to the central nervous system (CNS), where lipid nanoparticles (solid lipid nanoparticles – SLN and nanostructured lip...

中文翻译:

实验设计 (DoE) 作为设计质量 (QbD) 工具,用于优化鼻到脑药物输送的脂质纳米粒子配方

鼻子到大脑的途径已被广泛研究,以改善药物对中枢神经系统(CNS)的靶向性,其中脂质纳米颗粒(固体脂质纳米颗粒 - SLN 和纳米结构唇...
更新日期:2023-12-29
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