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Evaluation of Secondary Cytoreduction Surgery in Platinum-Resistant Ovarian Cancer Patients Within Three-Line Recurrent: A Multicenter, Randomized Controlled Study.
Journal of Gynecologic Oncology ( IF 3.9 ) Pub Date : 2023-10-30 , DOI: 10.3802/jgo.2024.35.e22
Tingting Chen 1, 2 , Junfen Xu 1, 2 , Bairong Xia 3 , Hui Wang 1, 2, 4 , Yuanming Shen 1, 2, 4
Affiliation  

Epithelial ovarian cancer is the leading cause of death among gynecological malignancies. Platinum resistance remains a dilemma and bottleneck in treatment, and salvage chemotherapy has limited effectiveness. Recently, the role of secondary cytoreductive surgery (SCS) in patients with platinum-resistant recurrent ovarian cancer (ROC) has caused attention especially in patients with oligometastases. However, there is neither high-quality evidence-based evidence nor standardized criteria for selecting SCS for patients with platinum-resistant ROC until now.

中文翻译:

三线复发内铂耐药卵巢癌患者二次细胞减灭术的评估:一项多中心、随机对照研究。

上皮性卵巢癌是妇科恶性肿瘤中死亡的主要原因。铂类耐药仍然是治疗的困境和瓶颈,挽救性化疗的效果有限。最近,二次细胞减灭术(SCS)在铂耐药复发性卵巢癌(ROC)患者中的作用引起了人们的关注,尤其是寡转移患者。然而,迄今为止,尚无高质量的循证证据,也没有标准化的标准为铂类耐药 ROC 患者选择 SCS。
更新日期:2023-10-30
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